RNA Details
Disease Name
liver cirrhosis
Tissue
liver
RNA Symbol
PALLD
RNA ID
RNA Type
circRNA
Alteration Pattern
up regulation
Species
homo sapiens
Detection Methods
qRT-PCR; bioinformatic analysis
Target
NA
Pathway
NA
PubMed ID
Title
Microarray profiling of circular RNAs and the potential regulatory role of hsa_circ_0071410 in the activated human hepatic stellate cell induced by irradiation
Year
2017
Function
"Compared with the normal HSC, 179 circRNAs were found to be up-regulated and 630 circRNAs were down-regulated in irradiated HSC (fold change >=2.0 and P<0.05). Six dysregulated circRNAs selected randomly were successfully verified by qRT-PCR. Bioinformatic analyses indicated that dysregulated circRNA might be involved in the cell response to irradiation and biological processes of hepatic fibrosis. Furthermore, inhibition of hsa_circ_0071410 increased the expression of miR-9-5p, resulting in the attenuation of irradiation induced HSC activation."
RNA Details
Disease Name
liver cirrhosis
Tissue
liver
RNA Symbol
PALLD
RNA ID
RNA Type
circRNA
Alteration Pattern
dysregulation
Species
homo sapiens
Detection Methods
qRT-PCR; microarray
Target
NA
Pathway
NA
PubMed ID
Title
Microarray profiling of circular RNAs and the potential regulatory role of hsa_circ_0071410 in the activated human hepatic stellate cell induced by irradiation
Year
2017
Function
"Furthermore, inhibition of hsa_circ_0071410 increased the expression of miR-9-5p, resulting in the attenuation of irradiation induced HSC activation."